Unmet need in CSU: What is Urticaria

What is Urticaria

Urticaria is a skin condition that is defined by the occurrence of red, itchy hives and/or angioedema (pronounced skin swelling of the deeper layers of the skin).1

It is a relatively common condition that can:

Affect up to 1 in 4 people at some point in their lives1

Affect twice as many women than men1

Become chronic, lasting between 1 and 5 years or even longer in severe cases1

There are different types of urticaria2

different types of urticaria

*Daily or almost daily occurrence of itchy hives, pronounced skin swelling or both, lasting for six weeks or more.
†Possible triggers include sunlight, water, heat and others. 

BE A LIFE CHANGER

71% reduction
in itch with Xolair®
300 mg vs baseline
at 12 weeks3†‡

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Treatment guidelines

International
EAACI/GA2LEN/EDF/WAO
guidelines recommend
omalizumab as an add-on
therapy for CSU patients with
an inadequate response to
H1-antihistamine treatment4

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*Patient verbatim and profile comes from hypothetical patient for illustrative purpose only

†Data from ASTERIA II; two other phase III studies (ASTERIA I and GLACIAL) were also conducted to assess efficacy and safety of Xolair® in inadequately controlled CSU patients

‡Xolair® 300mg vs. baseline at 12 weeks; p<0.001 vs placebo.

References: 1. Maurer M et al. Allergy 2011;66:317–330. 2. Zuberbier T et al. Allergy 2014;69(7):868–887. 3. Maurer M, et al. N Engl J Med 2013;368:924-935. 4. Zuberbier T et al. Allergy 2014; 69:868-887 

NP4 code: GLDEIM/IGE025E/0181

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